Paediatric Inflammatory Multisystem Syndrome(PIMS-TS) – UPSC Prelims

Paediatric Inflammatory Multisystem Syndrome(PIMS-TS):
  • PIMS-TS is also known as a multisystem inflammatory syndrome in children (MIS-C).
  • It is a rare condition associated with SARS-CoV-2 infection.
  • Caused by: It is not known what triggers the condition. But it is thought to be a rare immune overreaction that occurs in children approximately four to six weeks after mild or asymptomatic SARS-CoV-2 infection.
  • Symptoms: It includes fever, rash, eye infection, and gastrointestinal symptoms (e.g. diarrhoea, stomach ache, nausea). In some rare cases, the condition can lead to multi-organ failure.
  • Diagnosis: Currently, MIS-C is diagnosed based on symptoms together with laboratory tests that look for signs of inflammation in the body.
  • Treatment: Treatments currently include anti-coagulation to curb blood clotting, IV immunoglobulin and anti-inflammatory drugs.
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